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Frida begins with the traumatic accident Frida Kahlo (Salma Hayek) suffered at the age of 18 when a car trolley collided with a bus she was riding. She is impaled by a metal pole and the injuries she sustained plague her for the rest of her life. To help her through convalescence, her father brings her a canvas upon which to start painting. Throughout the film, a scene starts as a painting, then slowly dissolves into a live-action scene with actors.